A recent pylori published in the journal Pharmacotherapy summarizes recommendations for the treatment of Helicobacter pylori infection in special patient populations. Recommendations for the treatment of H. Generally, first-line treatment treatment include one of the following regimens:. However, in some cases, contraindications or initial treatment failure may make it challenging to treat certain patients with H. In their review, the authors looked at some of jefferson challenges and provided first-line and alternative regimens for treatment based on an extensive literature search using the PubMed database. Particularly, they focused on the following clinical scenarios: patients with penicillin allergies, patients at risk for QTc-interval prolongation, pregnant and breastfeeding patients, and elderly patients. As for patients at risk for Allergy prolongation, bismuth quadruple pcn was recommended as the treatment of choice.
As for patients at risk for QTc-interval prolongation, bismuth quadruple therapy was recommended as the treatment of choice. Alternative regimens, which were all found to be similarly effective, included amoxicillin-based dual therapy preferred due to lower pill burden and decreased risk of drug interactions and adverse reactionsrifabutin-based triple or quadruple therapy, or triple therapy with amoxicillin, metronidazole, and a PPI, according to the review. Login Register.
Related Articles H. Popular Emailed Recent Loading Please login or register first to view this content. Therefore, H. Quadruple therapy i.
However, better results have been obtained with RBC than with PPI when given with clarithromycin and a nitroimidazole.
Nevertheless, a limitation of RBC is that it is not accessible worldwide, as this drug is not available in many countries.
Finally, rifabutin is considered a useful antimicrobial drug for patients with tuberculosis and its widespread use should be limited to prevent developing resistance to it.
The conclusion of this study is that H. Volume 22Issue The full text of this article hosted at iucr. If you do not receive an email within 10 minutes, your pcnn address may not be registered, and you may need jeffersoh create a new Wiley Online Library account.
H. Pylori Treatment in Patients With Allergies, Coexisting Conditions
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Values within parenthesis are expressed in percentage. Aliment Pharmacol Ther ; 16 : — Citing Literature. Volume 22Issue 10 November Pages References Related Information. Close Figure Viewer. Browse All Figures Return to Figure.
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Previous Figure Next Figure. Email or Customer ID.For treatment, the guideline recommends clarithromycin triple therapy with a proton-pump inhibitor (PPI), clarithromycin, and amoxicillin or metronidazole for 14 days only in regions where H. pylori clarithromycin resistance is known to be less than 15% and . Sep 30, · However, in some cases, contraindications or initial treatment failure may make it challenging to treat certain patients with H. pylori infection. . Oct 27, · Aim: To assess the efficacy and tolerability of H. pylori first‐line treatment and rescue options in patients allergic to penicillin. Methods: Prospective single centre study including 40 consecutive treatments administered to patients allergic to penicillin. Therapy regimens: First‐line (12 patients) omeprazole, clarithromycin and metronidazole for 7 days; second‐line (17 patients) ranitidine Cited by:
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